Believing that he can cure cancer by freezing, Dr. Kravaal places his dying patient in an underground ice chamber carved out from a surrounding glacier. The patient's nephew, Bob Adams, and local officials visit Kravaal's laboratory, suspecting foul play. To prevent his patient from dying and himself from getting arrested, Kravaal attempts to scare them away with a powerful drug, but it renders everyone unconscious.
Ten years later, Dr. Tim Mason and his assistant, Judith Blair, arrive in a small Canadian village to find records of Dr. Kravaal's experiments. They discover the ice chamber containing the frozen bodies of Dr. Kravaal and the others. After reviving them, Kravaal realizes that the drug could be the cure for cancer, but Bob Adams, in frustration, destroys the formula. With Dr. Mason's assistance, Kravaal uses the others as test subjects until he recreates the formula. After they die from his experiments, the mad doctor attempts to experiment on Miss Blair, but a search party arrives in time. Kravaal is shot, but dies knowing that Dr. Mason will use his findings for the good of humanity.