During a harsh winter, Jack Griffin arrives at a remote Sussex inn, his entire face covered in bandages and wearing thick black glasses. The innkeeper, shocked by his appearance, agrees to give him a room. Inside the room, he sets up scientific equipment and starts experimenting with a drug he developed called monocane. When Griffin causes chaos at the inn and is told to leave, he reveals that he has become invisible and is driven insane. He goes on a violent rampage and tries to force a fellow doctor to help him take over the world, defying his well-intentioned mentor Dr. Cranley. When Flora, his former love, pleads with him to turn himself in, he laughs and runs off, shouting "The whole world is my hiding place."